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BILATERAL OBSTRUCTIVE UROPATHYR.A.S. HEMAT, MB;BCh, FRCSI, Dip. Urol. UCL
Bladder obstruction can affect caldesmon expression in the detrusor. Bladder obstruction induces hypertrophy is associated with a dedifferentiation of the smooth muscle cells of the bladder. In the early phases of bladder obstruction detrusor hypertrophy leads to an increase in detrusor pressure.
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